Vitamin K2 helps relief Nocturnal Leg Cramps (NLCs)
For the phenomenon of the leg cramps in older individuals at night, the research team led by Dr. Tan Jing from the Hematology Department of the Third People’s Hospital of Chengdu applied natural source vitamin K2 (MK-7) for treatment and achieved significant results. The research findings were recently published in the top international authoritative medical journal JAMA Internal Medicine.

At present, there is no proven safe and effective treatment for nocturnal leg cramps (NLCs), so it is crucial to seek safe and effective methods for managing NLCs.
The multicenter, double-blind, placebo-controlled randomized clinical trial conducted by Dr. Tan Jing’s research team involved 199 participants 65 years and older who had 2 or more times NLCs during a 2-week screening. Eligible participants were randomly assigned in a 1:1 ratio and orally administered 180μg of Vitamin K2 (MK-7) product or placebo capsules every night for 8 weeks. The average times, duration and severity of NLCs per week were recorded. The results showed that during the intervention period, the average weekly cramps frequency of the vitamin K2 (MK-7) group decreased to 0.96, while the placebo group remained at 3.63, also no adverse events related to the use of vitamin K2 (MK-7) were found.

This randomized clinical trial showed that naturally sourced vitamin K2 supplements significantly reduced the frequency, intensity and duration of NLCs in the older individuals with good safety profile.
Source:
https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2825457
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